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The results of a study by Dr. Denise Sloan (VA Boston Healthcare System) showed that written exposure therapy (WET) was noninferior to prolonged exposure therapy (PE) in PTSD symptom change and was associated with significantly less attrition. The findings suggest that WET may transcend previously observed barriers to PTSD treatment for both patients and clinicians (Written Exposure Therapy vs Prolonged Exposure Therapy in the Treatment of Posttraumatic Stress Disorder: A Randomized Clinical Trial | Psychiatry and Behavioral Health | JAMA Psychiatry | JAMA Network). The study was highlighted this week in the New York Times (Writing Therapy Shows Promise for PTSD - The New York Times (nytimes.com). Dr. Sloan has a history of Merit Review funding in CSRD. She is a staff psychologist at VA Boston and Associate Director, Behavioral Science Division of the National Center for PTSD.
Clinical Science Research and Development (CSRD) has selected 32 Principal Investigators for the Spring 2023 funding cycle. Applications were released on Wednesday, August 16, 2023, in eRA Commons Just-in-Time (JIT).
Join us in congratulating the 11 applicants selected for Career Development Awards and 21 applicants selected for Merit Awards whose innovative studies will improve the lives of Veterans!
Career Development selectees for Spring 2023 cycle:
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Berey, Benjamin Leonard, PhD, Providence, ''Applying Mixed Methods to Identify Links between Cannabis Use and Sleep Behaviors with Ramifications for Veterans Clinical Health Outcomes''
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Berlow, Yosef Alfred, MD, PhD, Providence, ''Modeling the Treatment Response of Transcranial Magnetic Stimulation for Depression''
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Bradley, Ellen R., MD, San Francisco, ''Examining ketamine effects on depression, neuroplasticity, and inflammation in Veterans with Parkinson’s disease''
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Chakravorty, Subhajit, MBBS, Philadelphia, ''The Genetic Architecture of co-occurring Insomnia and Alcohol Use Disorder''
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Chanderraj, Rishi, MD, Ann Arbor, ''Impact of anti-anaerobic antibiotics on clinical outcomes and the microbiome in hospitalized Veterans''
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Hunt, Christopher, PhD, San Diego, ''Inhibitory Learning as a Novel Mechanism of Prolonged Exposure: An Investigation of Laboratory and Mobile Health Measures''
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Krauss, Alison, PhD, Temple, ''Predicting Suicide Behavior Among High-Risk Veterans Using a Multimethod Assessment of Reactive Aggression''
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Levis, Maxwell Eli Joshua, PhD, White River Junction, ''Using big data to develop universal and selective suicide prevention strategies''
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Nair, Devika, MD, Nashville, ''Activation for Self-Care Needs in Older Adults with Chronic Kidney Disease: ACTIVE SENIORS with CKD''
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Nokes, Brandon Thomas, MD, San Diego, ''The Role of Negative Effort Dependence as a Targetable Mechanism of Upper Airway Collapse in Sleep Disordered Breathing''
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Yu, Wesley Y., MD, Portland, ''BOOST: Better Oncology Outcomes Through Statin Treatment''
Merit selectees for Spring 2023 cycle:
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Bedimo, Roger, MD, Dallas, “Characteristics and Determinants of Post-COVID Neurocognitive Dysfunction''
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Byers, Amy Lynn, PhD, San Francisco, ''Lethal Suicide Methods in Aging Veterans: Associated Profiles, Trajectories, and Transitions Informing Attempts''
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Chen, Yabing, PhD, Birmingham, ''BCCMA: Integrating Nutrition and Metabolic Monitors to Mitigate Cardiometabolic Disparities in our Veterans (VA-iMITIGATE)''
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Degutis, Joseph Michael, PhD, Boston, ''Characterizing the behavioral and neural mechanisms of inhibitory control dysfunction in PTSD''
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Eklund, Elizabeth Ann, MD, Chicago, ''Identifying molecular markers that predict relapse after therapy discontinuation in chronic myeloid leukemia''
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Harle, Katia, PhD, San Diego, ''The Neurocomputational mechanisms of anhedonia and their role in predicting alcohol use and treatment responsiveness in Veterans with Alcohol Use Disorder''
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Jain, Manu, MD, Chicago, ''Mitochondrial metabolism as a therapeutic target in pulmonary fibrosis''
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John, Binu, MD, Miami, ''Addition of F18-Piflufolastat PET/CT to Cross-Sectional Imaging for the Staging and Management of Hepatocellular Carcinoma''
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Kambhampati, Suman, MD, Kansas City, ''Benefit of Venetoclax Addition (Benefit VA) in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)''
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Kheradmand, Farrah, MD, Houston, ''Harnessing Allo-immunity to Enhance Immune Checkpoint Inhibitor Responses in Advanced NSCLC''
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Lee, Mary, MD, Washington, DC, ''Low Intensity Focused Ultrasound For Chronic Pain: High Resolution Targeting Of The Human Insula''
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Loftis, Jennifer M., PhD, Portland, ''Immune-mediated pathogenic mechanisms of Neuro-PASC in Veterans''
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Maxwell, Kara N., MD, PhD, Philadelphia, ''Mutational processes underlying tumor development in United States Veterans''
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Nguyen, Kim-Lien T., MD, Los Angeles, ''Tailoring Stress Cardiac MRI for Women with Ischemic Heart Disease''
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Platanias, Leonidas C., MD, PhD, Chicago, ''Signaling Pathways and Therapeutic Targeting of Leukemic Cells''
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Ranjan, Ravi, MD, PhD, Salt Lake City, ''Computational Modeling Guided Ablation for Atrial Flutteris''
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Shahrara, Shiva, PhD, Chicago, ''Establishing novel therapeutic strategies to target RA pannus formation''
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Strigo, Irina A., PhD, San Francisco, ''The role of expectation in the pain-trauma co-morbidity among Veterans''
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Suvannasankha, Attaya, MD, Indianapolis, ''Preclinical Validation of Adjuvant Fingolimod to Increase Efficacy of Proteasome Inhibitors for Treatment of Multiple Myeloma''
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Tkaczyk, Eric R., MD, PhD, Nashville, ''Quantitative assessment of cutaneous systemic sclerosis''
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Trembley, Janeen H., PhD, Minneapolis, ''Protein kinase CK2 in prostate cancer progression and clinical potential for therapy''
(A planned monthly feature of this newsletter that will include tidbits about the Just-In-Time (JIT) process that may assist research offices and Principal Investigators completing JIT, with the ultimate goal of receiving ORD funding.)
August: Animal Subjects Research Review Area
For the Animal Subjects Research Review JIT area, the station should not upload or submit anything into eRA Commons JIT. All of the processing for this JIT area is being handled outside of eRA. Eventually, it will all be done from inside IRBNet. However, until that mechanism is fully functional all correspondence for JIT is being handled via emails through Alice Huang (alice.huang@va.gov). Once the secondary review is completed, Dr. Huang will submit a record of the secondary review process into eRA and approve the JIT area in eRA JIT. To allow time for the secondary review process, you are encouraged to send the protocol to Dr. Huang as soon as it has been approved by the IACUC and the applicable certification statements have been signed. There is no need to wait for other JIT documents to be ready.
For JIT related inquiries, please contact: vhacoblcsrdjit@va.gov.
- Dr. Jayanthi Sankar will be attending the Pain/Opioid CORE in-person meeting on Monday and Tuesday, September 18-19, 2023, in Minneapolis, Minnesota.
- Dr. Miriam Smyth will be attending the 8th Annual San Antonio (Texas) Combat PTSD Conference October 17-18, 2023.
The CSRD Data Monitoring Committee (DMC), that provides data and safety monitoring for CSRD-funded projects, is seeking biostatisticians, neurologists, and other new members. For more information, please contact DMC Manager Dr. Tamara Paine.at Tamara.Paine@va.gov.
Career Development: VHACADEReview@va.gov
Clinical Trials: clin-review@va.gov
General Mailbox: VHABLRD-CSRD@va.gov (Please note this is a shared mailbox that should be used for general questions that will be triaged by staff to the appropriate individual.)
Just-in-Time Mailbox: VHACOBLCSRDJIT@va.gov
Scientific Portfolio/Program Managers: BLR&D and CSR&D Contact Information (va.gov)
Newsletter: Lucindia.Shouse@va.gov
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