New DNA Biosensor Could Unlock Powerful, Low-Cost Clinical Diagnostics

nist

View as a Web Page

News

New DNA Biosensor Could Unlock Powerful, Low-Cost Clinical Diagnostics

Illustration of a DNA biosensor device for clinical diagnostics that is the size and shape of a smartphone.

DNA can signal the presence of or predisposition to a slew of diseases, including cancer. The ability to flag down these clues, known as biomarkers, allows medical professionals to make critical early diagnoses and provide personalized treatments. The typical methods of screening can be laborious, expensive or limited in what they can uncover. A new biosensor chip that boasts an accurate and inexpensive design may increase accessibility to high-quality diagnostics.

The biosensor, developed by researchers at the National Institute of Standards and Technology (NIST), Brown University and the French government-funded research institute CEA-Leti, identifies biomarkers by measuring how binding occurs between DNA strands and the device. What sets it apart from other similar sensors is its modular design, which lowers costs by making it easier to mass produce and allowing the most expensive components to be reused.

Read More

IN CASE YOU MISSED IT

Microscope image shows the word "NIST" in gold letters on a strand of human hair.

NIST Finds a Sweet New Way to Print Microchip Patterns on Curvy Surfaces

Nov. 25, 2022
NIST scientist Gary Zabow had never intended to use candy in his lab. It was only as a last resort that he had even tried burying microscopic magnetic dots in hardened chunks of sugar — hard candy, basically — and sending these sweet packages to colleagues in a biomedical lab.

Read More