In a clinical trial of people with advanced lung cancer, palliative care delivered via telehealth was just as effective at improving their quality of life as care received in person.
In a clinical trial, people with advanced cancer and cachexia (a wasting syndrome that leads to loss of muscle and fat) treated with the experimental drug ponsegromab gained 2 to 6 pounds over 12 weeks, depending on the dose they received. Those treated with the placebo lost an average of 1 pound over the same period.
NCI launched a precision medicine clinical trial to test new treatment combinations targeting specific genetic changes in the cancer cells of people with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). The trial aims to accelerate the discovery of more tailored treatments for these aggressive cancers.
This page describes the new MyeloMATCH clinical trials and lists the trials currently open to people with AML or MDS, plus how to find more information.
Clinical trial results identified what experts say should now be the first treatment for advanced leiomyosarcoma. In the trial, the combination of trabectedin (Yondelis) and doxorubicin improved survival by a median of 9 months.
This video features Krishnan R. Patel, M.D., a researcher at NCI who leads the FOCUS RT trial for people with early prostate cancer. Dr. Patel addresses several questions people may have about the radiation therapy trial for people with a single tumor confined to the prostate gland.
Clinical Trials Information for Patients and Caregivers
You may wonder if clinical trials cost money and who pays for them. Many clinical trial costs are covered by the sponsor of the study, your insurance plan (if you have one), and sometimes you will have out-of-pocket costs. Before you join a study, ask the study coordinator which costs are covered and which are not.
Each clinical trial that is funded by the federal government must be reviewed by scientists from relevant fields before you can enroll. This expert review ensures that the trial is based on sound science. If you take part in a clinical trial, your safety will be protected through the informed consent process, careful review and approval of the clinical trial protocol, and ongoing monitoring.
This phase 2 trial is testing a type of precision radiotherapy called stereotactic body radiation therapy (SBRT) in people with early-stage prostate cancer. People in the trial will undergo several diagnostic and imaging tests to determine the precise location of the tumor in the prostate and guide the course of radiation treatment. Doctors want to see if targeting the exact tumor location with SBRT may be effective and lead to fewer side effects.
This phase 2 clinical trial is testing three chemotherapy combinations to treat younger people with intermediate risk AML. These patients usually receive cytarabine and daunorubicin. This standard combination will be tested against two experimental combinations. Doctors will determine if experimental combinations work better than the standard treatment at killing cancer cells.
This phase 1b/2 trial is testing a five-drug regimen called ViPOR for people with B-cell lymphoma that has either come back or not responded to treatment. In the first part of the trial, doctors will determine if these drugs are safe and effective when given together. In the second part, they will see how many people see their cancer shrink or go away entirely.
