KRAS Inhibitors | Second Cancers | Dense Breasts, 08/28/2024

National Cancer Institute

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Cancer Information Highlights
From the National Cancer Institute
Updating you about cancer causes, prevention, screening, treatment, coping, and more
 
New from NCI
Can Chemo Help KRAS Inhibitors Work Better Against Pancreatic Cancer?
A chemotherapy bag hanging and a woman receiving treatment sitting in a chair.   Two new studies in mice show that adding chemotherapy to the experimental KRAS inhibitor MRTX1133 greatly reduced tumor growth and spread compared with either treatment alone.

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Understanding the Risk of Second Cancers After CAR T-Cell Therapy
T cell attacking cancer cell   In late 2023, the Food and Drug Administration (FDA) announced it was looking into cases of second cancers following treatment with CAR T-cell therapies. In this Q&A, NCI’s Dr. Stephanie Goff explains what’s known about the issue, stressing that second cancers “of any kind are rare.”

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Engineering Cancer Cells to Short-Circuit Treatment Resistance
a double helix with a chunk missing   Scientists have developed a way to treat cancer by taking advantage of tumors’ ability to quickly evolve and turning it against them. It involves making some tumor cells resistant to a specific treatment from the get-go.

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Dense Breasts

This updated page answers questions that are often asked about dense breasts. Topics include what dense breasts are, how you know if you have dense breasts, whether they are a risk factor for breast cancer, and what you should do if you have them.

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Acute Lymphoblastic Leukemia (ALL) Treatment

ALL is a type of blood cancer that comes on quickly and is fast growing. This updated page has information about ALL in adults, including causes and risk factors, symptoms, diagnosis, and treatment options.

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Vorasidenib Citrate Approved for Brain Tumors in Adults and Children

FDA has approved vorasidenib citrate (Voranigo) to treat brain tumors called astrocytomas and oligodendrogliomas in adults and children aged 12 and older. It is used after surgery in people whose cancer has certain IDH1 or IDH2 gene changes.

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Cancer Information Specialist talks on a headset   Information specialists at NCI’s Cancer Information Service (CIS), NCI's contact center, are available to help answer your cancer-related questions in English and Spanish. This page tells you how to reach us by phone, chat, or email.