For some people with early-stage cervical cancer, a simple hysterectomy may be as safe and effective as a radical hysterectomy, results from the SHAPE trial show.
The Food and Drug Administration (FDA) has approved lifileucel (Amtagvi) for certain advanced melanomas. This is the first cancer treatment that uses immune cells called tumor-infiltrating lymphocytes, or TILs.
Early results from a clinical trial show that people with advanced kidney cancer can use a new form of nivolumab (Opdivo) that is given as an injection under the skin, which is quicker and easier than an IV.
NCI has launched the Virtual Clinical Trials Office, a centralized team of support staff that will work remotely to assist NCI-Designated Comprehensive Cancer Centers and community practices with their clinical trials activities.
The ALCHEMIST clinical trials are a group of randomized clinical trials for people with early-stage non-small cell lung cancer whose tumors have been completely removed by surgery. People entering the study will have their tumor tissue tested to see if one of the drugs being studied targets a specific biomarker found in their tumors. Those with targeted biomarkers are treated in a trial specific to their tumors. Those who do not have a targeted biomarker are assigned to treatment with immunotherapy. This revised and streamlined page explains what the trials are and which ones are recruiting participants.
Adine Usher felt a bump on her left breast. Her mammogram just 2 months earlier was normal, but she still had a sinking feeling. It was breast cancer. “Doctors don’t make advances or have any kind of impact without patients participating in trials," Adine said.
Clinical Trials Information for Patients and Caregivers
Before you join a study or clinical trial, ask about which costs might be paid by your health plan and which costs might be covered by the study. This web page explains the different type of costs and expectations for who might pay for which costs.
This phase 2 clinical trial compares treatment with the targeted drugs neratinib and palbociclib versus neratinib alone for people with gynecologic or other solid tumors with high levels of HER2. Giving neratinib with palbociclib may shrink or stabilize cancers that have too much HER2.
This phase 2 trial is testing a device that uses electrical signals to help strengthen the pelvic floor. Men treated for prostate cancer frequently develop urinary incontinence. Doctors want to see if the device will help improve the symptoms of urinary incontinence in men experiencing this side effect.
This phase 3 clinical trial will test an internet-based program of coping skills for pain in adults with cancer. People undergoing adjuvant treatment or who have finished cancer treatment but are still having cancer-related pain will be randomly assigned to receive the internet-based program along with standard pain care, or standard pain care alone. Doctors want to see if the internet-based program reduces the pain and the amount of interference in daily life it causes.
