In a clinical trial, people being treated for cancer who took part in live virtual mind–body fitness classes were less likely to be hospitalized and had shorter stays when they were than people who did not take the classes.
NCI’s James H. Doroshow, M.D., reflects on NCI-MATCH, a first-of-its-kind precision medicine cancer trial, and gives an overview of three new related trials that are being launched now: ComboMATCH, MyeloMATCH, and iMATCH.
A phase I clinical trial testing an experimental vaccine for recurrent respiratory papillomatosis, a problem marked by frequent growths in the airways caused by a chronic HPV infection, found that growths stopped in about half of people who received the vaccine.
Clinical Trials Information for Patients and Caregivers
Clinical trials are designed to work in phases that follow strict guidelines, including who can participate. Learning how clinical trials work can help you decide if you want to join.
In this video, researchers in the NCI Community Oncology Research Program (NCORP) talk about how the network makes it easier for people from diverse settings to enroll in cancer clinical trials closer to home.
This phase 1/2 trial is testing an experimental drug called eltanexor combined with an FDA-approved drug (decitabine-cedazuridine [Inqovi]) for people with myelodysplastic syndromes at high risk of turning into leukemia. In the first part of the trial, doctors will study the safety and determine the best dose to give to patients. Then they will treat participants at that dose and assess responses to the treatment.
This phase 1 trial will test a CAR T-cell therapy that targets a protein called GPC3 found on the surface of advanced liver cancer cells. People with liver cancer that tests positive for GPC3 who have not improved with chemotherapy will have the procedure. Doctors want to see if CAR T-cell therapy using T cells modified to detect GPC3 is safe.
This phase 1 trial will test a combination of six drugs for people with B-cell lymphoma that has either come back or not responded to treatment. Doctors want to see if these drugs are safe and effective when given together.
