Clinical Trials Update from NCI, October 2023

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Clinical Trials
Updates from the National Cancer Institute
 
Clinical Trials News
 
Kidney cancer scan  

SBRT Emerging as an Important Treatment for Early-Stage Kidney Cancer


Stereotactic body radiotherapy was effective in people with localized kidney cancer who weren’t able to have surgery to remove their tumor, a clinical trial has shown. No patients had their cancer start growing or died from cancer over the next 5 years.

 
ASPS-scan  

Trial Results Confirm Effectiveness of Atezolizumab Against a Rare Sarcoma


Treatment with atezolizumab (Tecentriq) shrank tumors in about 40% of people with alveolar soft part sarcoma, including one complete response, new clinical trial findings show. Some people were later able to stop treatment without the cancer returning.

 

Doctor-holding-colonoscope  

Is AI Ready to Play a Leading Role in Colorectal Cancer Screening?


Using computer-aided detection (CAD) during a colonoscopy doesn’t help doctors find the growths most likely to become colorectal cancer, two studies find. Researchers agreed that CAD, which is aided by artificial intelligence (AI) technology, needs further refinement.

 

Enrolling in a Clinical Trial in Rural America


In 2021, Kellie felt an acute pain in her right shoulder. She ignored it, thinking it was a strained muscle. Over the next year, the pain became stronger. When she started coughing up blood in the summer of 2022, she took action and had a chest x-ray. Read about Kellie’s diagnosis and how she was able to participate in a clinical trial near her home in rural South Carolina.

 

The Ups and Downs of a Rare Blood Cancer Won’t Stop One Resilient Patient

 

Luis Miguel Cruz has been sharing his cancer journey on social media since he was diagnosed with lymphoma in 2020. Cruz, who is from the Dominican Republic, came to the NIH Clinical Center for treatment for a rare type of blood cancer. Read his story about participating in a clinical trial and sharing his experiences online.

 
 
Clinical Trials Information for Patients and Caregivers
 

NIH Clinical Research Trials and You: The Basics


The NIH Clinical Research Trials and You website is a resource for people who want to learn more about clinical trials. This page provides answers to common questions about taking part in a clinical trial.

 

NCI's Clinical Trials Programs and Initiatives


This page describes NCI’s clinical trial programs and initiatives and explains how they help support a national infrastructure for clinical cancer research. These programs and initiatives help make cancer clinical trials more responsive to the rapid advances being made in cancer science.

 
Clinical trials search  

Find NCI-Supported Clinical Trials


Use our search form to find a clinical trial or other research study that may be right for you or a loved one.

 
 
NCI-Supported Clinical Trials That Are Recruiting Patients 
 

TMIST: Study Comparing Digital Mammograms (2-D) with Tomosynthesis Mammograms (3-D)


TMIST (Tomosynthesis Mammographic Imaging Screening Trial) is a randomized breast cancer screening study that compares two types of Food and Drug Administration–approved digital mammograms for their ability to reduce advanced breast cancer. The trial will help researchers learn about the best way to find breast cancer in women who have no symptoms.

 

FORTE Colorectal Cancer Prevention Trial


The FORTE (Five- or Ten-Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps) study will help determine if certain people can wait for a follow-up colonoscopy after a routine screening colonoscopy. It is a randomized clinical trial for people who have one or two small, noncancerous polyps (adenomas) removed during a routine screening colonoscopy.

 

ComboMATCH Precision Medicine Clinical Trials


ComboMATCH (Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice) is a series of precision medicine cancer treatment clinical trials. These trials will help determine whether treating cancer using combinations of targeted therapies based on specific genetic changes found in people’s tumors is effective.