For people with acute lymphoblastic leukemia (ALL) who are in remission, even when there is no trace of their disease, adding blinatumomab (Blincyto) to their treatment can help them live longer. Learn about the results from this large clinical trial.
Many young women diagnosed with early-stage breast cancer want to become pregnant in the future. New clinical trial results suggests that these women may be able to pause their hormone therapy for up to 2 years as they try to get pregnant without raising the risk of the cancer coming back.
Results from an NCI-funded clinical trial show that the combination of ribociclib (Kisqali) and hormone therapy was much better at shrinking metastatic tumors than standard chemotherapy for younger women with advanced breast cancer.
Clinical Trials Information for Patients and Caregivers
Experts review clinical trial protocols before studies are launched to make sure they are based on sound science. All clinical trials funded by the federal government must go through this type of review.
Most clinical trials run as planned from beginning to end. But sometimes trials are stopped early. This page discusses some of the reasons why clinical trials end early.
This phase 2 trial will test the effectiveness of dostarlimab (Jemperli), an immunotherapy drug, as an initial treatment in people with advanced solid tumors with a genetic change called deficient mismatch repair. Doctors want to see if upfront treatment with dostarlimab for 6 months will shrink or completely kill the tumor before any other treatments are needed.
This phase 3 trial studies how well bupropion (Wellbutrin) works in reducing cancer-related fatigue in stage 1 to 3 breast cancer survivors. Bupropion is used to treat depression, as well as to help people quit smoking. But researchers want to learn if it may also improve cancer-related fatigue.
This phase 2 trial will test Minnelide in people with a rare and highly aggressive type of pancreatic cancer (adenosquamous carcinoma of the pancreas). Minnelide rapidly releases a molecule into the bloodstream that slows cancer cell growth and causes cancer cells to die. Doctors want to see if treatment with this experimental drug will help people with this type of pancreatic cancer.
