RNA biology has emerged as one of the most influential areas in modern biology and biomedicine. NCI is home to a wide spectrum of work in RNA biology ranging from elucidating RNA biogenesis and structure, identifying functions for various classes of RNAs, establishing the role of RNA in disease, and exploring RNA-based and RNA-targeted therapies. The goal of this retreat, hosted by the NCI RNA Biology Initiative, is to enhance interactions amongst PIs, fellows and staff working on RNA and to foster new collaborations and synergies amongst NIH laboratories interested in RNA biology. The retreat will feature our keynote speaker, Julie M. Claycomb, Ph.D., University of Toronto and several talks selected from submitted abstracts. Fellows, staff scientists and trainees (including Leidos contractors) are encouraged to submit an abstract for consideration.  We also hope to catalyze interactions between basic and clinician researchers at this retreat.