Clinical Trials Update from NCI, July 2022

National Cancer Institute banner

Having trouble viewing this email? View it as a Web page.

Bookmark and Share

Clinical Trials
Updates from the National Cancer Institute
Clinical Trials News

Targeted Therapy Improves Survival for Metastatic “HER2-Low” Breast Cancer

People with metastatic breast cancer whose tumors had low levels of HER2 protein lived longer after treatment with trastuzumab deruxtecan (Enhertu) than those treated with standard chemotherapy, results of the DESTINY-Breast04 clinical trial show.

MRI image  

Ifosfamide May Be Better Treatment for Some People with Ewing Sarcoma

New findings from the first large, randomized clinical trial to compare chemotherapy regimens for relapsed or treatment-resistant Ewing sarcoma could help doctors and patients select treatments. In the study, patients who received ifosfamide (Ifex) lived longer than those who received a combination of two other chemotherapy drugs.


Targeted Therapy Is Better than Chemo for Some Kids with Brain Cancer

The combination of dabrafenib (Tafinlar) and trametinib (Mekinist) was safer and better than standard chemotherapy at shrinking low-grade glioma tumors and keeping them at bay in some children with a genetic mutation known as BRAF V600 in their cancer cells. The treatment also seemed effective for children with high-grade glioma, according to results from a phase 2 trial.

Clinical Trials Information for Patients and Caregivers

Federal Government Health Insurance Programs

Some federal programs may help pay the costs of care in clinical trials for eligible beneficiaries. This page describes those programs and who they can help.


Video: Should You Join a Clinical Trial?

This video explains three reasons why a patient may want to consider joining a cancer clinical trial.

Search for a clinical trial  

Find NCI-Supported Clinical Trials

Use our search form to find a clinical trial or other research study that may be right for you or a loved one.

NCI-Supported Clinical Trials That Are Recruiting Patients 

Five- or Ten-Year Colonoscopy for People with One or Two Polyps

In this phase 3 trial, people who have had one or two small benign polyps removed during a routine screening colonoscopy will be randomly assigned to undergo their next colonoscopy at 5 or 10 years. The findings from the trial will help determine if people who have had up to two small polyps removed during a routine colonoscopy can wait 10 years for another one.


Six-Drug Combination for Relapsed or Resistant B-Cell Lymphoma

This phase 1 trial will test a combination of six drugs for people with B-cell lymphoma that has either come back or not responded to treatment. Doctors want to see if these drugs are safe and effective against B-cell lymphoma when given together.


Evaluating Immune Responses after COVID Vaccination in Young People with Cancer

This study will examine the immune responses after COVID vaccination in people with cancer aged 6 months to 37 years. Scientists want to see how the immune systems of young people with cancer respond to the COIVD vaccine.