Immunotherapy for Eye Cancer | Checkpoint Inhibitors | Clinical Trials, Cancer Information Highlights, 05/12/2021

National Cancer Institute

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Cancer Information Highlights
From the National Cancer Institute
Updating you about cancer causes, prevention, screening, treatment, coping, and more
New from NCI
Immunotherapy Drug Improves Survival in Advanced Melanoma in the Eye
View from a microscope showing T cells killing uveal melanoma cells after treatment with tebentafusp.   In a large trial, the immunotherapy drug tebentafusp helped people with uveal melanoma live longer than people who received other treatments for the disease. Uveal melanoma is an aggressive cancer of the eye. 
Long-Term Side Effects of Immune Checkpoint Inhibitors

Although doctors know about the short-term side effects of immune checkpoint inhibitors, less is known about the long-term ones. A new study details the chronic side effects of these drugs in people who received them as part of treatment for melanoma.
Today’s Clinical Trials Are Tomorrow’s Standard of Care
NCA50 logog   Taking part in a clinical trial today can help other people in the future. Read Adine Usher’s story about taking part in the TAILORx breast cancer clinical trial.
Two-Drug Combination Shows Promise against Small Cell Lung Cancer
two stylized DNA strands, one with a break in it   Researchers found that a combination of the drugs topotecan (Hycamtin) and berzosertib can shrink tumors in some people with small cell lung cancer. Small cell lung cancer is the most aggressive form of lung cancer.
Targeted Therapy May Mean Less Radiation for Children and Teens with Hodgkin Lymphoma

In a recent study, a treatment regimen using brentuximab vedotin (Adcetris) instead of the usual chemotherapy drug allowed some children and teens with advanced Hodgkin lymphoma to avoid radiation therapy. Radiation therapy can cause long-term health problems.
What Is Cancer?

This updated page explains what cancer is, how cancer cells differ from normal cells, and genetic changes that cause cancer to grow and spread.

PDQ Updates
Cancer Pain

We’ve revised our PDQ summary on cancer pain with updated information about the side effects of opioid treatment.

FDA Approvals

The Food and Drug Administration approval for pembrolizumab (Keytruda) now includes first-line treatment of stomach or gastroesophageal junction (GEJ) cancer. The drug is used in people whose cancer is HER2 positive and has spread or cannot be treated with surgery.
Also of Interest
Protect Your Skin from Sunlight

The sun, sunlamps, and tanning booths all give off UV radiation that can lead to skin cancer. Visit this page to learn how to protect yourself from skin damage.

Last Days of Life

This page includes information about care at the end of life to help people with cancer and their families understand what to expect during this time. The page includes common symptoms and questions about treatment. 

Contact Us for Help

Information specialists at NCI’s Cancer Information Service (CIS), NCI's contact center, are available to help answer your cancer-related questions in English and Spanish. Reach us by phone, chat, or email.