Clinical Trials Update from NCI, January 2021

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Clinical Trials
Updates from the National Cancer Institute
 
Clinical Trials News
 
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Relugolix Approval Expected to Alter Treatment for Advanced Prostate Cancer


A large clinical trial showed that relugolix (Orgovyx) was more effective at reducing testosterone levels than another common treatment. FDA’s recent approval of relugolix is expected to change the treatment of men with advanced prostate cancer. 

 
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Trial Tests Abemaciclib As New Option for Early-Stage Breast Cancer


The drug abemaciclib (Verzenio) may be a new treatment option for people with the most common type of breast cancer. New study findings suggest that it can reduce the risk of the cancer returning.

 
 
Clinical Trials Information for Patients and Caregivers
 

Insurance Coverage and Clinical Trials


Federal law requires most health insurance plans to cover routine patient care costs in clinical trials under certain conditions. Learn which types of trials are covered and specific types of costs that are not.

 

How to Work with Your Health Insurance Plan


There are ways to learn if your health plan covers routine patient care costs in a clinical trial. This page offers some ideas about who to contact for help, questions to ask, and information to collect and keep if you decide to take part in a trial. 

 
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Find NCI-Supported Clinical Trials


Use our search form to find a clinical trial or other research study that may be right for you or a loved one.

 
 
NCI-Supported Clinical Trials That Are Recruiting Patients 
 

Combining Drug Therapies for Relapsed or Progressive T-Cell Malignancies


This phase 1 trial will study the dosing and safety of a combination of four drugs in people with T-cell malignancies that have either come back after or got worse during previous treatment. NCI researchers will determine a safe dose of the four-drug combination and assess the safety of the drugs when given together. Researchers will also see if this treatment will cause tumors to shrink.

 

Surgery for Gastrointestinal Stromal Tumors (GISTs)


This study will collect tumor tissue and examine how long after surgery patients with surgically removed GISTs remain free of disease. Researchers need donated tumor tissue to develop new therapies and learn more about the role of certain genes in the development of GIST and treatment resistance.

 

Combination Immunotherapy for Metastatic Breast Cancer


This phase 1 study will test a combination of immunotherapy and other drugs for people with breast cancer that has spread to other parts of the body. Researchers want to see if the combination of four drugs, which includes immunotherapy, can shrink metastatic breast cancer tumors.