February NCI Office of Advocacy Relations Update

National Cancer Institute sent this bulletin at 02/03/2020 03:41 PM EST
National Cancer Institute

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You are subscribed to the Office of Advocacy Relations Update from the National Cancer Institute. Read highlights of the latest news and upcoming events happening at NCI. 

 

Upcoming Events

National Cancer Advisory Board (NCAB) Meeting, February 11, 2020

Clinical Trials and Translational Research Advisory Committee (CTAC) Meeting, March 12, 2020
 

Note: Videocasts for advisory board meetings will be available at https://videocast.nih.gov/ the day of the meeting and will be archived shortly after for viewing on demand.

Recent Cancer Currents Posts

  

Off Target: Investigating the Abscopal Effect as a Treatment for Cancer (January 28, 2020)

In people with cancer, the abscopal effect occurs when radiation—or another type of localized therapy—shrinks a targeted tumor but also causes untreated tumors in the body to shrink. Researchers are trying to better understand this phenomenon and take advantage of it to improve cancer therapy.

Changes in Metabolism Help Melanomas Spread (January 21, 2020)

Melanoma cells that metastasize to other parts of the body produce high levels of a protein called MCT1, a new study in mice has found. Blocking MCT1 with an investigational drug, AZD3965, led to fewer and smaller metastatic tumors.

Enfortumab Vedotin Approved for Recurrent Bladder Cancer (January 14, 2020)

Enfortumab vedotin-ejfv (Padcev) has been approved for people with advanced bladder cancer. FDA granted the drug accelerated approval for cancers that have progressed despite previous treatments.

For Metastatic HER2-Positive Breast Cancer, New Treatments Emerge (January 8, 2020)

Tucatinib improved survival for women in the HER2CLIMB trial, including some whose cancer had spread to the brain. Trastuzumab deruxtecan improved survival and shrank many tumors in the DESTINY-Breast01 trial, which led to its accelerated approval.

Brain Cancer Cells Hijack Gene “On Switches” to Drive Tumor Growth (January 6, 2020)

Glioblastoma cells sneak many copies of a key oncogene into circular pieces of DNA. In a new NCI-funded study, scientists found that the cells also slip several different genetic “on switches” into these DNA circles, helping to fuel the cancer’s growth.

 

Read more news at the Cancer Currents blog.