NCI is redesigning the way patients and oncologists find information and learn about cancer clinical trials by making NCI-supported trials available through an application programming interface (API).
Clinical trials to test new cancer treatments involve a series of steps, called phases. Learn about the different clinical trial phases, the purpose of each phase, and the number of people who take part.
Randomization, in which people are assigned to groups by chance alone, helps prevent bias in research. Learn more about bias and how randomization works in clinical trials.
This phase l/ll study is for patients with solid tumors or lymphomas that have come back after a period of improvement. Methoxyamine and temozolomide work in different ways to stop the growth of tumor cells. Methoxyamine may also increase the effectiveness of temozolomide against tumor cells. Giving them together may kill more tumor cells.
This phase l trial is for patients who have solid tumors, including colorectal cancer, that has spread. Selumetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Cyclosporine may stimulate or suppress the immune system and stop tumor cells from growing. Giving selumetinib and cyclosporine may be a better treatment for colorectal cancer or other solid tumors.
This phase II trial is for patients with uveal melanoma that spread to other parts of the body or has returned near the same place. Glembatumumab vedotin may shrink the tumor by binding to tumor cells and delivering tumor-killing substances to them.
