Three-dimensional structure of the bacterium Bdellovibrio bacteriovorus, including membrane (purple), nucleoid (yellow), ribosomes (dark red), and dense granules (green). Bdellovibrio is a predatory bacteria species that can invade other bacteria. It kills and eats its prey from the inside and then reproduces.
This image of beta-galactosidase at 3.2 Å resolution illustrates the differential effect that electron radiation (orange rays) has on different parts of proteins (green) during high-resolution cryo-electron microscopy (cryo-EM) imaging. Acidic side chains, like glutamate (bottom, red atoms), break down first, before more basic side chains, like histidine (top, blue atoms).
Artist's model of a dendritic cell engulfing an HIV-infected T cell. Based on three-dimensional focused ion beam scanning electron microscopy (FIB-SEM) data.
HIV viruses (red) on surface of an HIV-infected macrophage. An electron micrograph of one section of the cell is shown. The structure was derived from a stack of images like these. Data from focused ion beam scanning electron microscopy (FIB-SEM).
Rendering of three-dimensional image stack showing HIV virions (red) localized on filopodial bridges between an infected T cell (gold) and uninfected fetal astrocyte (blue) in vitro. Data from focused ion beam scanning electron microscopy (FIB-SEM).
Three-dimensional structure of the intersection of two cells lining the small intestine (orange), shown with the stack of electron microscopy images that the structure was derived from. Data from focused ion beam scanning electron microscopy (FIB-SEM).
Three-dimensional structure of a single mitochondrion in a cell lining the small intestine, shown with the stack of electron micrographs that it was derived from. Data from focused ion beam scanning electron microscopy (FIB-SEM).
Segmentation of a mitochondrion (blue and green), neurofilaments and microtubules (purple) from mouse neural tissue. Shown with an electron microscopy image of one section from which the three-dimensional segmentation was derived. Data from electron tomography.
Three-dimensional structure of the metabolic enzyme pyruvate dehydrogenase (PDH). PDH turns pyruvate, which comes from sugar, into acetyl CoA. This is an important step in creating energy for the cell. An outer structure of E1 subunits (purple) surround a core of E2 subunits (green). One unit of catalytically active portions of PDH are shown in red, green, and yellow.
