White Mulberry Leaf: Science and Safety

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U.S. Department of Health & Human Services  /  National Institutes of Health

Background 

  • White mulberry is native to China but can be found throughout the world in temperate and tropical climates.
  • In traditional Chinese medicine, mulberry leaves are used to treat diabetes, cough, sore throats, fever, and bronchitis.
  • Preparations from white mulberry leaves are sold as dietary supplements for controlling weight and blood glucose.

What Have We Learned? 

  • Several studies suggest that white mulberry may reduce elevated blood glucose levels, but some of these studies were preliminary or were not conducted in people.

What Do We Know About Safety? 

  • White mulberry leaf has been used in studies lasting up to 12 weeks without serious harmful effects.
  • The most common side effect is digestive upset, including bloating, constipation, gas, and loose stools.
  • There is a potential risk for low blood sugar if white mulberry leaf is taken with diabetes medications.

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