Passionflower: Science and Safety

Click here to view in browser.

U.S. Department of Health & Human Services  /  National Institutes of Health

Background 

  • Passionflower is a climbing vine that is native to the southeastern United States and Central and South America. 
  • This herb is promoted as a dietary supplement for anxiety, sleep problems, and other conditions.

How Much Do We Know? 

  • Passionflower’s effects on health conditions have not been extensively studied. 

What Have We Learned? 

  • A small amount of research suggests that passionflower might help to reduce nonspecific anxiety and anxiety before a surgical or dental procedure, but conclusions are not definite. 
  • There’s not enough evidence to say whether passionflower is helpful for any other health conditions. 

What Do We Know About Safety? 

  • Up to 800 mg daily of a passionflower extract has been used with apparent safety in studies lasting up to 8 weeks, but it may cause side effects such as drowsiness and confusion in some people. 
  • Whether it’s safe to use passionflower topically (on the skin) is not known.

Find out more