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WASHINGTON—The U.S. Department of Energy (DOE) has announced funding to advance the Genesis Mission’s efforts to tackle the nation’s most complex science and technology challenges. This includes a $293 million Request for Application (RFA),“The Genesis Mission: Transforming Science and Energy with AI.” Through this RFA, DOE invites interdisciplinary teams to leverage novel AI models and frameworks to address over 20 national challenges spanning advanced manufacturing, biotechnology, critical materials, nuclear energy, and quantum information science.
The challenges include a topic on Unleashing Subsurface Strategic Energy Assets. Under this topic, applicants will be asked to leverage AI tools to better understand chemical and hydrologic transport in the subsurface, evolution of fractures in the upper crust, and/or control of subsurface fractures.
The RFA is open to interdisciplinary teams from DOE National Laboratories, U.S. industry, and academia. Phase I awards will range from $500,000 to $750,000 and support a nine-month project period. Phase II awards will range from $6 million to $15 million over a three-year project period. Teams may apply directly to either phase in FY 2026, and successful Phase I teams will be eligible to compete for larger Phase II awards in future cycles.
Phase I applications and Phase II letters of intent are due April 28, 2026. Phase II applications are due May 19, 2026. DOE will hold an informational webinar about this RFA on Thursday, March 26, 2026, at 3:00 pm ET; registration is required.
For full eligibility, application instructions, and challenge details, see the official RFA. Registration instructions and other details will be posted on this funding opportunities page.
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