CSMS # 67780481 - Deployment UPDATE Related to U.S. Food and Drug Administration (FDA) Supplemental Guide, DRAFT Version 2.6

U.S. Customs and Border Protection sent this bulletin at 02/17/2026 02:34 PM EST

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CSMS # 67780481 - Deployment UPDATE Related to U.S. Food and Drug Administration (FDA) Supplemental Guide, DRAFT Version 2.6

This is an update regarding the deployment related to FDA Supplemental Guide, version 2.6, announced in CSMS #66347264 and 66836343.

Section 12.3 of the draft FDA Supplemental Guide, version 2.6 has been updated to clarify that if the FDA Process Indicator Code = A, then the Government Agency Processing Code must = CSU.

If not met, this validation triggers a reject. Please test in CERTIFICATION, as needed.

Due to this clarification, the PRODUCTION deployment date related to FDA SG 2.6 has been rescheduled for March 10, 2026.

The updated U.S. Food and Drug Administration (FDA) Supplemental Guide (SG) draft version 2.6 (dated February 4, 2026) is posted in the ‘Draft Chapters: Future Capabilities’ section of CBP.gov.

Refer to the attachment for a visual of the scheduled FDA changes.

For questions about the changes to SG 2.6 contact FDA ACE Support: ACE_Support@fda.hhs.gov

Related Messages: 66836343, 66347264

FDA Visual of scheduled changes.pdf

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