
Nematode Can Rebuild Muscle and Neurons After Complete Degradation
What can scientists learn
about human neurodegenerative disease from a major soybean pest? It’s not a
trick question; the answer lies in the soybean cyst nematode, one of two
classes of microscopic roundworms known to lose and then regain mobility as
part of their life cycle.
“This is an animal that
basically undergoes neurodegeneration, including nearly complete muscle
atrophy, and then is able to reverse it in later development. From a human
health perspective, I’m excited about the possibilities this could hold,” says
Nathan Schroeder, assistant professor in the Department of Crop Sciences at the
University of Illinois and corresponding author on the new study.
Applying these findings to
human neurodegenerative disease may still be a long way off, but the research
could lead to important practical outcomes for soybean pest management. Soybean
cyst nematode is the among the worst soybean pests in the United States and the
world, causing more than a billion dollars in yield loss annually. Exploiting
this mechanism, which appears to be unique to soybean cyst and root knot
nematode, another finding in the study, could be very good news for the soybean
industry.
NIFA supports this
research through the Hatch Act.
Read more at the University of Illinois News. USDA Photo.
|