UK REACH ebulletin: Public consultation on alternatives | Defra persistent organic pollutants review

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Public consultation on alternatives: call for comments

DEADLINE: 4 October 2022

HSE has received an application for authorisation for the following substances/use:


Reference: AFA014-01

Substances: 4-(1,1,3,3-tetramethylbutyl)phenol, ethoxylated (OPnEO) and 4-Nonylphenol, branched and linear, ethoxylated (NPnEO)

Use: Use of OPnEO and NPnEO in 10 in vitro diagnostic (IVD) assays used for example in Clinical Chemistry (CC) and Drug Monitoring (DM) products


Article 64 in the UK REACH Regulation makes provisions for HSE to obtain and use additional information on possible alternatives or technologies as part of the opinion forming process.


HSE has announced a public consultation for this application.


Any third parties with an interest in the application are strongly encouraged to share any relevant information.


Scientific and technical information on possible alternatives or technologies should be submitted directly to HSE using the commenting webform and templates by 4 October 2022.


Non-confidential comments will be published on HSE’s website.


Visit the HSE website for details of adopted opinions, granted UK REACH authorisations and in-progress applications.

Persistent organic pollutants (POPs) exemption review – request for information

DEADLINE: 19 August 2022

Defra is currently undertaking a review of whether certain POPs, controlled by the Stockholm Convention, are still being manufactured and/or used in the UK (under currently available exemptions for specific products and industrial processes).


The specific POPs being reviewed are:

  • Decabromodiphenyl ether (decaBDE)
  • Perfluorooctanoic acid (PFOA), its salts and PFOA-related compounds
  • Perfluorooctane sulfonic acid, its salts, and its derivatives, (PFOS)
  • Short chain chlorinated paraffins (SCCPs)

As part of the review, Defra is inviting industry to provide information on the use of these POPs. They will also contact organisations known to have registered use of the exemptions. 


This information will help Defra and the Stockholm Convention understand the continued need for specific exemptions.


Read the review, with information on how to respond, on GOV.UK:

Review of statutory exemptions for permitted uses of persistent organic pollutants (POPs)


The formal deadline for comments is 12 August 2022. However, DEFRA will continue to accept responses up to 19 August 2022.


Please notify if a late submission is expected via email to

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