CRD live online training event: human health endocrine disruption of pesticides and biocides

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Live online training event: human health endocrine disruption of pesticides and biocides

7 and 8 April 2022

This training event will focus on the toxicological endocrine disruption (ED) assessment of pesticide and biocide active substances and biocide products and will present the current evaluation approach used by CRD (HSE).

 

Topics covered

  • ED criteria for pesticide and biocide active substances and associated ECHA/EFSA guidance

  • Overview of toxicology ED assessment scheme for biocide/pesticide active substances
    • General approach and information sources for adversity and activity
    • Specificity of adverse effects
    • OECD Conceptual Framework for testing and assessment of EDs

  • Templates, spreadsheets and assessment guiding principles

  • Assessment of T (thyroid) modality, including data gaps, MoA (mode of action) analysis and DNT (developmental neurotoxicity) considerations

  • Case studies to illustrate T modality assessment with potential different outcomes

  • Assessment of EAS (estrogen-androgen-steroidogenesis) modalities, including deficient datasets, data gaps and MoA analysis

  • Case studies to illustrate EAS modalities’ assessment with potential different outcomes

  • Endocrine disruption assessment of co-formulants in biocide products

Who should attend?

 

Those who already carry out toxicological endocrine disruptor assessments of pesticide and biocide substances and biocide products or have an interest in the evaluation approach used by HSE (CRD).

 

Registration

 

If you wish to register for the training event, please visit our booking page and complete an online registration form.

 

The closing date for registration is 30 March 2022.

 

 

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