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The Antibiotic Use and Stewardship in Minnesota: 2025 Update on Progress and Opportunities (PDF) report summarizes data that the Minnesota Department of Health (MDH) uses to describe the state of antibiotic use and stewardship in Minnesota. The report includes current and past measures of outpatient and hospital antibiotic use and metrics, and presents who prescribes and receives antibiotics in Minnesota. The antibiotic stewardship program data show trends in hospital and nursing home core element implementation, as well as data on outpatient stewardship practices.
- In 2023, Minnesotans received fewer outpatient antibiotics than the U.S. overall and Minnesota’s state-level prescribing rate is lower than that of many other states.
- Like the national trend, overall outpatient antibiotic prescribing rates in Minnesota decreased from 2019 to 2020, falling 19.8% in the first year of the COVID-19 pandemic. Overall rates began to rise in 2021 and, in 2023, returned much closer to pre-pandemic levels.
- Minnesota’s top 10% antibiotic prescribers by volume were responsible for 35% of the total antibiotic volume prescribed in 2022. These prescribers were most commonly family medicine providers.
- 38% of Minnesota’s high-volume prescribers in 2022 maintained their status in the high-volume prescribing category consistently from 2018 through 2021. Moreover, most high-volume prescribers (68%) in 2022 were also high-volume prescribers in 2021.
- Use of first-line antibiotics for uncomplicated UTIs improved in 2020–2021. Nearly half (49.5%) of patients treated during this period received a first-line antibiotic. Compared with 2018–2019, uncomplicated UTI cases in 2020–2021 were more likely to be treated with a recommended first-line option (OR 1.38; 99.99% CI: 1.35–1.41).
- In Minnesota, 69% of acute care hospitals implemented four or more priority core elements in 2023, an increase from 35% in 2021.
U.S. and Minnesota outpatient antibiotic prescribing rates per 1,000 population, 2019–2023
MDH is proud to recognize 71 hospitals and 15 long-term care facilities on our Antibiotic Stewardship Honor Roll! We invite you to join your peers in publicly demonstrating your commitment to antibiotic stewardship by applying for the Minnesota Antibiotic Stewardship (AS) Honor Roll:
The Honor Roll was designed to recognize antibiotic stewardship programs and the associated organizational commitments to improving antibiotic use and prescribing practices. This program aims to:
- Encourage AS commitment from the highest level of administration to prescribers and caregivers.
- Share AS activities with health professionals and the public, with the aims of highlighting new ideas and encouraging facility-to-facility engagement.
- Provide incentive for AS program improvement through mentorship in both individual facilities and statewide.
- Publicize the importance of using antibiotics judiciously.
For more information, visit Minnesota Antibiotic Stewardship Honor Roll or email Health.Stewardship@state.mn.us.
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