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Minnesota Department of Health
March 25, 2022
Updated Recommendations: Second Doses of COVID-19 Vaccine
Two doses are needed for the primary series of the Pfizer and Moderna COVID-19 vaccines. Your health care provider or the person giving you the vaccine will let you know when to get your second dose.
- The second dose of the Pfizer vaccine is given 3-8 weeks after the first dose.
- The second dose of the Moderna vaccine is given 4-8 weeks after the second dose.
New research suggests that people ages 12 to 64, particularly males age 12 to 39, may benefit from getting their second dose eight weeks after the first dose. A longer time between the first and second doses may increase the effectiveness of these vaccines, and minimize the small risk of heart problems, including myocarditis and pericarditis.
Some people should still get their second doses at three or four weeks. People ages 5 through 11 years, people 65 years and older, people at risk of severe disease, or anyone needing to develop protection quickly because of high levels of COVID-19 in their community should get the second dose of Pfizer COVID-19 vaccine three weeks after the first dose, or the second dose of Moderna COVID-19 vaccine four weeks after the first dose.
People who have already received their primary series and got the two doses three or four weeks apart still have good protection against COVID-19—especially if they have received a booster dose—and do not need to repeat any doses.
Learn more:
Minnesota Department of Health (MDH) Materials
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