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Minnesota Department of Health
February 23, 2022
On Feb. 22, 2022, the Center of Disease Control and Prevention (CDC) updated its COVID-19 vaccination guidance with additional information to help vaccine providers determine the optimal interval between the first and second dose of an mRNA vaccine series, based on the individual patient.
The updated recommendation allows for people 12 to 64 years of age, particularly males 12 to 39 years, to receive their second mRNA COVID-19 (Pfizer and Moderna) primary series dose up to 8 weeks after their first dose. This new recommendation is based on the latest safety and effectiveness data, CDC: Myocarditis and COVID-19 Vaccine Intervals: International Data and Policies. Extending the time interval between primary mRNA COVID-19 vaccine doses to 8 weeks may help lower the (small) risk of myocarditis and pericarditis, which has been associated mostly among adolescent and young adult males with mRNA COVID-19 vaccination. It may also help increase how long protection lasts against COVID-19.
However, this update does not apply to everyone. Providers should continue to recommend the 3-week or 4-week intervals for Pfizer and Moderna products respectively for people who are moderately or severely immunocompromised, adults 65 years and older, and others who may need early protection due to concern about an increased risk of severe illness from COVID-19 or high levels of community transmission.
This updated guidance is specific to the mRNA (Pfizer-BioNTech or Moderna) COVID-19 vaccine primary series and is only for patients who have not yet started their series or who haven’t yet received their second dose. The interval between COVID-19 mRNA vaccine doses is best determined by considering the balance of risks and benefits, based on the person’s age and health conditions.
For additional details, including updated vaccination tables, refer to the CDC: Interim Clinical Considerations for Use of COVID-19 Vaccines: Primary series. Providers may also want to attend the Clinician Outreach and Communication Activity (COCA) call: Updated Guidance for Clinicians on COVID-19 Vaccines on Thursday, Feb. 24, 2022, from 1:00-2:00 p.m. CST.
We are updating our MDH resources with this recent change and they will be posted on COVID-19 Vaccine Providers soon.
Johnson & Johnson COVID-19 vaccine is not currently available to order in MIIC, but we do have doses available via redistribution. We encourage providers who may be able to use doses of Johnson & Johnson vaccine to request them via our SmartSheet tool: COVID-19 Vaccine Available for Redistribution.
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