COVID-19 Vaccine Provider Weekly Updates

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COVID-19 Vaccine Provider Weekly Updates

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Minnesota Department of Health

February 15, 2022


Updates to the interim clinical considerations

On Feb. 11, the Centers for Disease Control and Prevention (CDC) updated their Interim Clinical Considerations for Use of COVID-19 Vaccines. Along with the updates below, the clinical considerations have been reorganized and many sections have been condensed.

People who are moderately or severely immunocompromised

  • Clarification of existing recommendation to receive a 3-dose mRNA vaccine primary series followed by a booster dose for a total of 4 doses.
  • New guidance to shorten the interval between completion of the mRNA vaccine primary series and the booster dose to at least 3 months (instead of 5 months).
    • Refer to Table 3 for a summary of the updated COVID-19 vaccination schedule for people who are immunocompromised.
  • New guidance for those who received the Janssen (Johnson & Johnson) COVID-19 vaccine primary series to receive an additional dose and a booster dose, for a total of 3 doses to be up to date.
    • Refer to Appendix B for additional information about completing schedules that have included the use of the Janssen COVID-19 vaccine in this population.

People who received monoclonal antibodies or convalescent plasma

  • COVID-19 vaccination can be given at any time following receipt of antibody products as part of COVID-19 treatment, post-exposure prophylaxis, or pre-exposure prophylaxis. Deferral periods for vaccination have been eliminated.

People who received COVID-19 vaccine outside the United States

  • Updated guidance on receiving a booster dose. Refer to Appendix E for additional details.

People with a history of myocarditis or pericarditis after an mRNA COVID-19 vaccine

We are updating MDH vaccine protocols, screening and agreement form, and provider guide with these recent changes and the updated resources will be posted on COVID-19 Vaccine Providers soon.


Importance of vaccinating immunocompromised

Providing an additional dose as part of the primary series followed by a booster dose for people who are moderately to severely immunocompromised is shown to provide improved protection against SARS-CoV-2 infection and hospitalization. Ensure you are administering all current recommended doses to keep them up to date.

People can self-attest to their moderately to severely immunocompromised status and receive COVID-19 vaccine doses wherever vaccines are offered. Vaccinators should not deny COVID-19 vaccination to a person due to lack of documentation.

Vaccinated people who are immunocompromised should be counseled about the potential for a reduced immune response to COVID-19 vaccines. They and their close contacts should continue to follow current prevention measures on CDC: How to Protect Yourself & Others.

President’s Day (Feb. 21) vaccine delivery hold

COVID-19 vaccines will not be delivered on Monday, Feb. 21 (President’s Day) due to the holiday. Regular delivery of COVID-19 vaccines will resume on Tuesday, Feb. 22.

Find previous bulletins at COVID-19 Vaccine Provider Updates.