 Which
antibiotic is properly matched to its antibiotic class?
a. Furazolidone – Oxasilodinone
b. Vancomycin – Ansamycin
c. Gentamicin – Glycopeptide
d. Tylosin – Polypeptide
e. Levofloxacin – Fluoroquinolone
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The answer is at the bottom of this newsletter.
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New Factsheets Available
Three new factsheets are available from the One Health Antibiotic Stewardship Collaborative.
Antibiotic Use and Resistance: Answers for Patients (PDF)
Antibiotic Use in Companion Animal Veterinary Practice (PDF)
Antimicrobial Use and Resistance Module: A tool to manage, use, and report hospital antibiotic use data (PDF)
2018 Minnesota Antibiotic Stewardship Conference for Healthcare Professionals
When: May 1, 2018
What: Free full-day conference focused on stewardship in ambulatory care settings!
Who: Relevant for prescribers, clinical staff, and pharmacists in outpatient medical clinics, emergency departments, and dental clinics. Administrators and those involved in patient engagement and quality improvement are also welcome to attend.
Where: Wilder Center, 451 Lexington Avenue North, Saint Paul, MN 55104
Registration: Antibiotic
Stewardship Conference: Focus on Ambulatory Care
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Updated Clostridium difficile treatment guidelines released
New publication focuses on fluoroquinolone use
- In a new publication, CDC antibiotic stewardship experts report that 5% of all fluoroquinolones prescribed for adults in doctor’s offices and emergency departments are unnecessary, and about 20% of all fluoroquinolone prescriptions in these settings are not recommended first-line treatment.
- Fluoroquinolones are associated with adverse events, such as musculoskeletal and nervous system damage and rising rates of fluoroquinolone resistance.
- Inappropriate prescribing of fluoroquinolones is common and occurs in situations when antibiotics are and are not indicated.
- Read the article. Clinical Infectious Diseases: Opportunities to Improve Fluoroquinolone Prescribing in the United States for Adult Ambulatory Care Visits
AVMA formalizes "antimicrobial stewardship" definition for veterinary medicine
- Reflective of the unique realities that characterize a diverse multispecies profession, American Veterinary Medical Association has released a definition of "antimicrobial stewardship" and has identified stewardship core principles.
- Read the definition and core principles. AVMA: Antimicrobial Stewardship Definition and Core Principles
Acinetobacter spp. isolated from healthy canine skin
- In a paper published in Veterinary Dermatology, researchers confirm the ability of Acinetobacter spp., including A. baumannii, to survive on canine skin.
- With growing resistance globally in human Acinetobacter isolates, awareness of this pathogen as a cause of canine infection should be heightened, and emphasis should continue to be placed on routine use of culture and susceptibility testing in companion animal medicine.
- Also evident from this study is the potential for canines to become carriers of Acinetobacter when in the care of infected owners or when employed in healthcare-based pet therapy.
- Read the abstract. Isolation and identification of Acinetobacter spp. from healthy canine skin.
World Health Organization releases first global report on antimicrobial resistance in healthcare
- With over 50 countries enrolled in the World Health Organization's (WHO) Global Antimicrobial Resistance Surveillance System (GLASS), we are one step closer to understanding the global problem of antimicrobial resistance.
- Resistance of common bacteria to important antibiotics varied significantly by country, highlighting the need for robust national surveillance systems.
- Covering 12 classes of antimicrobials, countries reported susceptibility profiles for Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Streptococcus pneumoniae, Salmonella spp, Neisseria gonorrhoeae, and Shigella spp.
- The GLASS report also describes status, funding, and structure of national surveillance systems for antimicrobial resistance.
- Read the report. WHO GLASS Report: 2016-2017 Early Implementation
Request for proposals: Institute for Antimicrobial Resistance Research and Education
- Association of Public and Land-Grant Universities (APLU) and Association of American Veterinary Medical Colleges (AAVMC) have released a request for proposals to establish an Institute for Antimicrobial Resistance Research and Education.
- Read the request for proposals, which are due on April 1, 2018. APLU-AAVMC Memorandum
- Learn about the APLU-AAVMC Joint Task Force and read the 2015 Report. APLU: Antibiotics and Agriculture
CDC Online Antibiotic Stewardship Training
- CDC has launched the first of a four-section web-based training course on Antibiotic Stewardship.
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Doctors,
nurse practitioners, physician assistants, certified health education
specialists, nurses, pharmacists, and public health practitioners with a
master’s degree in public health are eligible to receive up to eight hours of free CE
for the entire course.
- Register for the training. CDC Training
on Antibiotic Stewardship: Section 1
May 1, 2018: MN Antibiotic Stewardship Conference
- This full-day conference in Saint Paul, MN, will be committed to antibiotic stewardship in ambulatory care settings.
- Conference is hosted by Minnesota Department of Health, Stratis Health, and Minnesota Hospital Association.
- Registration is now open. See the conference details webpage.
Antibiotic Resistance: Policy Challenges and Solutions Lecture Series
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 e. Levofloxacin – Fluoroquinolone
Fluoroquinolone antibiotics used in healthcare include levofloxacin, ciprofloxacin, and moxifloxacin. Veterinary fluoroquinolones include enrofloxacin, orbifloxacin, marbofloxacin, and ciprofloxacin. Each veterinary drug has species-specific approval (or lack thereof) and labeling.
Rising rates of fluoroquinolone resistance and adverse effects on individual patients have ensured the increased scrutiny of fluoroquinolones in all health disciplines. Fluoroquinolones are effective against a range of Gram-negative organisms and some Gram-positive aerobes, including intracellular pathogens.
See above for news of a new publication about fluoroquinolone overprescribing in outpatient healthcare settings.
Curious about fluoroquinolone resistance in Minnesota? Have a look at the State Antibiogram developed annually by the Minnesota Department of Health.
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