HARP Update: New Reference Exposure Levels (RELs) for Four Substances with Isocyanate Functional Groups

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August 18, 2025

HARP Update

New Reference Exposure Levels (RELs) for Four Substances with Isocyanate Functional Groups


The California Air Resources Board (CARB) has released updated health tables for the Hot Spots Analysis and Reporting Program (HARP) Air Dispersion Modeling and Risk Tool (ADMRT), Risk Assessment Standalone Tool (RAST) and Emission Inventory Module (EIM). 

The new REL values are as follows

Substance Pollutant ID  Acute REL (μg/m3) Chronic REL (μg/m3) 8-hour REL (μg/m3)
Aliphatic polyisocyanate 160994683 4.5 4.0 x 10-1 8.0 x 10-1
Hexamethylene-1,6-diisocyanate homopolymer 3779633 4.5 4.0 x 10-1 8.0 x 10-1
Hexane, 1,6-diisocyanato-, homopolymer 28182812 4.5 4.0 x 10-1 8.0 x 10-1
Hexane, 1,6-diisocyanato-, homopolymer, polyethylene-polypropylene glycol monobutyl ether-blocked 125252473 4.5 4.0 x 10-1 8.0 x 10-1

 

To get the new health database, select the “Help > Check for Updates” feature in the main menu of each program.  This feature will automatically download and update the health databases.  Once downloaded, restart each program to use the new health databases.

If you have questions or concerns please mail HARP staff at harp@arb.ca.gov.


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