This update is being sent to members of the Wisconsin Travel Health Network.
Changes in Travel Requirements for 2025
Real ID, European travel authorization, and new options for passport renewal
Real ID
Staring May 7, 2025, all air travelers 18 years and older will need to be REAL ID compliant. REAL ID-compliant cards are driver licenses or state-issued ID cards marked with a star in the top right corner. Travelers can learn about REAL ID on the Wisconsin Department of Transportation’s website.
ETIAS
Starting in 2025, visa-exempt nationals traveling to a number of European countries will be required to enroll in the European Travel Information and Authorization System (ETIAS). Most ETIAS applications are processed in minutes; however, it is possible that applications will take longer (between four and 30 days). Advise travelers to apply for ETIAS authorization well in advance of their trips.
Passport renewal
In late 2024, the Department of State announced their new online passport renewal system. Americans can renew their passports through a secure online system to process their new passports more quickly. Travelers can find application details, including the documents needed, on the Department of State’s website.
CDC Travel Health Notices for International Travelers
Level 4 – Avoid All Travel
None at this time.
Level 3 – Reconsider Nonessential Travel
None at this time.
Level 2 – Practice Enhanced Precautions
Clade I Mpox in Central and Eastern Africa (updated February 10) A level 2 travel health notice was issued for an outbreak of clade I mpox in Central and Eastern Africa. There is ongoing person-to-person transmission of mpox in Burundi, Central African Republic, Democratic Republic of the Congo (DRC), Kenya, the Republic of the Congo, Rwanda, Uganda, and Zambia. Mpox vaccination prior to travel is recommended for people who anticipate the following sexual activities during travel to countries with ongoing person-to-person mpox transmission: sex with a new partner; sex at a commercial sex venue; sex or intimate contact in exchange for money, goods, drugs, or other trade; or sex in association with a large public event.
Ebola in Uganda (updated February 6) There is a level 2 travel health notice for Sudan virus disease (SVD) in Uganda due to an outbreak in the Kampala, Mbale, and Wakiso areas. SVD is a type of Ebola disease caused by infection with the Sudan virus. Travelers to Uganda should avoid contact with sick people with symptoms of SVD, blood and other body fluids, semen from men who have recovered from an Ebola disease, and dead bodies; visiting health care facilities or traditional healers; participating in funerals or burial practices; handling or eating bats or nonhuman primates and their fluids; or going in area where bats live, such as mines or caves. Travelers are encouraged to watch their health for symptoms of SVD while in an outbreak area and for 21 days after leaving.
Global Polio (updated January 14) A number of countries in Africa, the eastern Mediterranean, Europe, and Southeast Asia are reporting higher-than-expected levels of poliovirus, resulting in a level 2 travel health notice issued on January 14. Providers should ensure travelers are up to date on their polio vaccines. Adult travelers are eligible to get an inactivated polio vaccine booster if they are going to a destination that has circulating poliovirus, have completed their routine polio vaccine series, and have not already received an adult booster dose.
Oropouche in Parts of Brazil and Panama (updated January 31) There is a level 2 travel health notice for Oropouche in Espírito Santo, Brazil, and Darién Province, Panama, due to current outbreaks of the illness in these areas. Travelers to these areas can lower their risk of getting infected with the Oropouche virus by taking steps to prevent bug bites, such as wearing long sleeves and pants and using insect repellents. Travelers should also condoms or abstain from sex during travel and for six weeks after returning from travel, as it is unknown if Oropouche can be spread through sex. Pregnant people should reconsider non-essential travel to these areas of Brazil and Panama. Oropouche is often mistaken for dengue; thus, clinicians should review the signs and symptoms of Oropouche.
Chikungunya in India (December 19, 2024) A level 2 travel health notice for an outbreak of chikungunya in the states of Maharashtra and Telangana, India was added late December. You can protect yourself by preventing mosquito bites, which includes using insect repellent; wearing long-sleeved shirts and pants; and staying in places with air conditioning or that have screens on the windows and doors. Vaccination against chikungunya is recommended for people aged 18 years or older who are traveling to a destination with a current chikungunya outbreak. Pregnant people should reconsider travel to the affected states, particularly if they are close to delivery. Travelers are encouraged to seek medical care if they develop fever, joint pain, headache, muscle pain, joint swelling, or rash, during or after travel.
Level 1 – Practice Usual Precautions
Oropouche in the Americas (Updated January 31)
Marburg in Tanzania (January 23)
Malaria in Ethiopia (January 17)
Histoplasmosis Cases Linked to Tourism in Costa Rica
January 31, 2025, the CDC (Centers for Disease Control and Prevention) Mycotic Diseases Branch (MDB) issued a call for cases to public health agencies of histoplasmosis linked to tourism in Venado Caves, Costa Rica. The MDB, in collaboration with public health officials in Georgia, Texas, and Washington, are investigating a cluster of 12 family members diagnosed with or reporting symptoms consistent with histoplasmosis. Individuals became mildly or moderately ill after participating in a tour of Venado Caves in Costa Rica, where bats and bat droppings were commonly sighted.
For additional information, please see the Communicable Disease Update regarding histoplasmosis cases linked to tourism in Costa Rica issued by the Wisconsin Department of Health Services on February 17, 2025.
Spring Break Travel Reminders
Spring break is approaching quickly. Travelers should prepare ahead of time to ensure they have a safe, healthy vacation. Individuals traveling internationally should make an appointment with their health care provider 4–6 weeks before departure to ensure they have any necessary destination-specific vaccines, information on health and safety concerns, and medications they may need. Travelers should bring copies of important documents like their passport and health insurance card if they’ll be abroad. Remind travelers to pack prescription medications that may be hard to find while traveling.
Providers should also caution travelers to avoid biting insects like midges, mosquitos, and ticks, particularly if they’ll be going to a tropical location. Travelers can pack insect repellant, wear long sleeves and pants, and stay in places with window and door screens to lower their risk.
Travelers might also be exposed to other health risks while on spring break and should take steps to protect themselves and others. Advise travelers to avoid raw food, street food, and water and ice that may be contaminated. Travelers should use sunscreen with SPF 15 or higher and reapply sunscreen every two hours. Remind travelers to follow safer sex practices, like using a condom or dam, to lower their risk of getting a sexually transmitted infection (STI). As evidenced by methanol poisonings of tourists earlier this year, drinks and substances consumed abroad can put travelers in dangerous situations. Counsel travelers to stay in groups and take note of where their nearest health care facilities are while away from home.
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Neglected Tropical Diseases
January 30 was Neglected Tropical Disease Day, a day dedicated to increasing awareness of a group of devastating diseases that have serious impacts on developing countries. Neglected Tropical Diseases (NTDs) are diseases that are common in low-income, tropical places but often don’t receive much attention globally.
NTDs are caused by viruses, bacteria, fungi, and parasites that thrive in places with limited clean water and poor sanitation. These include diseases like leprosy, rabies, Chagas disease, onchocerciasis (river blindness), scabies, and yaws.
Climate change is making it more challenging to control and manage the spread of NTDs. Rising temperatures and changes in weather patterns are also shifting the spread of many vector-borne diseases, increasing the risk of introducing these diseases to unprepared areas.
Travelers can protect themselves from NTDs by talking about travel plans with their provider, wearing long sleeves and protective clothing, avoiding water and ice in areas where it may be contaminated, and getting any necessary destination-specific vaccines.
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Disease Spotlight: COVID-19
It’s been five years since the beginning of the COVID-19 pandemic, but the virus continues to impact global health and safety. As case numbers around the world climb during respiratory season, travelers should be mindful of COVID-19 prevention and treatments so they can protect themselves and those around them.
COVID-19 is a respiratory disease caused by the SARS-CoV-2 virus. It can be very contagious and spreads quickly. COVID-19 most often causes respiratory symptoms that can feel much like a cold, the flu, or pneumonia. Although SARS-CoV-2 primarily attacks the lungs and respiratory system, the virus can also attack other parts of the body. Most people with COVID-19 have mild symptoms, but some people become severely ill, especially those over age 65 and those with certain underlying medical conditions, such as blood disorders, cancer, cerebrovascular disease, chronic kidney, liver, or lung disease, cystic fibrosis, diabetes, heart conditions, and immunodeficiency.
What are the symptoms?
People with COVID-19 can experience a wide range of symptoms. Most symptoms will be mild, but some can be severe and lead to hospitalization or death.
A person may have COVID-19 if they have any of these symptoms:
- Cough (new onset or worsening of chronic cough)
- Shortness of breath
- Fever or chills
- Sore throat
- Congestion or runny nose
- Muscle or body aches
- Headache
- New loss of taste or smell
How is it spread?
COVID-19 spreads when an infected person breathes out droplets and very small particles that contain the virus. Other people can breathe in these droplets and particles, or these droplets and particles can land on others' eyes, nose, or mouth, which can lead to infection with the SARS-CoV-2 virus.
Anyone infected with COVID-19 can spread it, even if they do not have symptoms. COVID-19 can even spread from people to animals in some situations.
How is it diagnosed?
In order to identify patients with a current SARS-CoV-2 infection, there are two main types of diagnostic tests capable of detecting SARS-CoV-2 in nasal or oral specimens:
- Nucleic acid amplification tests (NAATs), including PCR tests, detect RNA from the SARS-CoV-2 virus and are considered the “gold standard” for COVID-19 tests, since they are more likely to detect the virus than antigen tests.
- Antigen tests detect antigens from the SARS-CoV-2 virus. They are considered rapid tests that usually produce results in 15–30 minutes. Positive results are accurate and reliable. However, in general, antigen tests are less likely to detect the virus than NAAT tests, especially when symptoms are not present. Therefore, a single negative antigen test cannot rule out infection. To be confident you do not have COVID-19, FDA recommends two negative antigen tests for individuals with symptoms or three antigen tests for those without symptoms, performed 48 hours apart.
Are there treatments for COVID-19?
The FDA has authorized or approved several antiviral medications for use in treating mild to moderate COVID-19 in people who are more likely to get very sick.
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Antiviral medications target specific parts of the virus to stop it from multiplying in the body once someone is infected, helping to prevent severe illness and death.
- The Infectious Diseases Society of America provides Guidelines on the Treatment and Management of Patients with COVID-19 for health care providers to help them work with their patients and determine the best treatment options for their patients. Several treatment options are available for treating COVID-19. They include:
| Treatment |
Who (Among people who are at high risk of getting sick) |
When |
How |
Nirmatrelvir with Ritonavir (Paxlovid) Antiviral |
Adults; children ages 12 years and older |
Start as soon as possible; must begin within 5 days of when symptoms start |
Taken at home by mouth (orally) |
Veklury (remdesivir) Antiviral |
Adults and children |
Start as soon as possible; must begin within 7 days of when symptoms start |
Intravenous (IV) infusions at a health care facility for 3 consecutive days |
Molnupiravir (Lagevrio) Antiviral |
Adults |
Start as soon as possible; must begin within 5 days of when symptoms start |
Taken at home by mouth (orally) |
Some treatments might have side effects or interact with other medications patients are taking. Side effects vary for each medication. For example, Paxlovid can cause a metallic taste in the mouth which goes away when patients stop taking the medication. Paxlovid is more likely to interact with other medications than other COVID-19 antivirals, but most people can still take it. Individuals should check with providers or pharmacists if they are taking other medications to ensure that COVID-19 treatments can be safely taken at the same time.
In the case of hospitalization, a health care provider might use other types of medications, depending on the level of illness. These could include medications to treat the virus, reduce an overactive immune response, or treat COVID-19 complications.
For those who have a weakened immune system, have received antiviral treatment, and continue to experience COVID-19 symptoms, a health care provider may recommend additional treatment, including convalescent plasma.
COVID-19 oral antiviral treatments are available for certain people at a lower cost. Patient assistance programs for Paxlovid, Veklury, and Lagevrio are available to people who are underinsured, uninsured, and who are on Medicare or Medicaid to lower their out-of-pocket costs. Patients can enroll in these programs to learn if they can receive assistance for specific medications, regardless of their insurance status.
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Good News in Travel Health
Jimmy Carter’s foundation, The Carter Center, has been working to eradicate the NTD Guinea worm disease. In 1986, 2.3 million people were affected by Guinea worm disease. Now, cases of Guinea worm have been decreased by more than 99.99%!
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