COVID-19 Vaccine Updates-Additional doses and Clinical Guidance Updates

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Immunization Program

Additional Doses in COVID-19 Vaccine Vials

At this time, given the COVID-19 public health emergency, FDA is advising that it is acceptable to use every full dose obtainable (the sixth, or possibly even a seventh) from each vial, pending resolution of the issue. However, since these are preservative free vials, it is critical to note that any further remaining liquid that does not constitute a full dose should not be pooled from multiple vials to create one dose.

Please be sure to adjust WIR inventory as needed, based on these instances. Inventory can be adjusted as follows:

  • Review and address any outstanding transfers and current inventory in WIR. It is important to make sure there are no outstanding transfers of vaccine and all inventory is accounted for prior to making adjustments.
  • Under manage inventory, select “show inventory.”
  • Select the applicable COVID site in the site dropdown to review the correct vaccine inventory.
  • Select the correct tradename and lot number by clicking the checkbox next to the applicable vaccine.
  • Click “modify quantity” in the upper right.
  • Modify the total doses in inventory, using “receipt of inventory” as the reason for the adjustment.
  • Click save.

Detailed instructions with screenshots can be found within Chapter 11 of the WIR user Manual. A recorded webinar regarding inventory management can also be found here.

WIR-Inventory Management

Important: Additional Clinical Guidance for COVID-19 Vaccine

CDC has issued Interim Considerations for Preparing for the Potential Management of Anaphylaxis at COVID-19 Vaccination Sites. Appropriate medical treatment for severe allergic reactions must be immediately available in the event that an acute anaphylactic reaction occurs following administration of Pfizer-BioNTech COVID-19 Vaccine.

Vaccination providers should also be reminded to review, implement, and consult CDC’s Interim Clinical Considerations for Use of Pfizer-BioNTech COVID-19 Vaccine. All ACIP recommendations related to COVID-19 vaccine can be found at ACIP COVID-19 Vaccine Recommendations | CDC.