Alcohol and Gut-Derived Inflammation

The National Institute on Alcohol Abuse and Alcoholism sent this bulletin at 12/13/2019 02:37 PM EST

Alcohol and Gut-Derived Inflammation

Alcohol promotes intestinal inflammation. This gut inflammation in turn can promote multiple organ dysfunctions and chronic disorders associated with alcohol consumption, including chronic liver disease, neurological disease, GI cancers, and inflammatory bowel syndrome. This review summarizes the mechanisms by which chronic alcohol intake leads to intestinal inflammation. Understanding these mechanisms of gut inflammation can aid in the discovery of therapeutic approaches to mitigate alcohol-induced organ damage.

This featured article was published in ARCR Volume 38 Number 2 (2017).

Alcohol Research: Current Reviews (ISSN: 2168–3492) is a peer-reviewed journal produced by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Opinions expressed in contributed articles do not necessarily reflect the views of NIAAA. The U.S. government does not endorse or favor any specific commercial product or commodity. Trade or proprietary names appearing in this publication are used only because they are considered essential in the context of the studies reported herein.

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