This letter sets out the scientific and public health rationale for the dosing schedule for the AstraZeneca vaccine and the change to the dosing schedule for the second dose of the Pfizer vaccine.
The Joint Committee on Vaccination and Immunisation (JCVI) has put forward a prioritisation scheme, as included in the Green Book Chapter 14a (tables 2 and 3) which is included.
The JCVI have also issued a short statement 'Optimising the COVID-19 vaccination programme for maximum short-term impact' which is also included.
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