Exposure Assessment and Control

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February 2018

Case Study

Industrial application of moisture cure urethane (MCU) coatings 

Isocyanates are a primary component of moisture cure polyurea (MCU) products.  Find out how we successfully characterised the isocyanate content in some of these products and then assessed the risks in a spray booth application scenario, working with the client to be as representative of real world conditions as possible.


MbOCA adopted opinion

ECHA have adopted the joint SEAC and RAC opinion on 2,2-dichloro-4,4-methylenedianiline (MbOCA). The report recommends a review period of 4 years for MbOCA use as a curing agent/ chain extender in cast polyurethane elastomer production.


Recommendations for those looking to use MbOCA beyond the 4 year review period must demonstrate the effectiveness of their risk management measures (RMM) by the implementation of a monitoring programme. These recommendations include (among others) twice yearly biological monitoring of workers and surface contamination analysis. Monitoring results shall then be used to review and improve the RMMs and operational conditions. The outcomes of these reviews must be documented and included in any subsequent authorisation review report submitted.


There is a UK Biological Monitoring Guidance Value for MbOCA (15 µmol/mol creatinine) and HSL offers biological monitoring.  Our data show that exposures have reduced over the past decades but that progress has stalled in recent years.  However, companies with good control practices are able to keep results below 3 µmol/mol creatinine (see our research paper).