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Thank you for your role in supporting access to therapeutics in Oregon. The Oregon Health Authority (OHA) appreciates your partnership as we continue navigating the federal allocation process. |
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Federal Allocations
Week of January 9th:
mAbs Allocation Cycle
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Evusheld (monthly): 2,412
Oral antivirals - Weekly (one week cycle)
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Lagevrio (molnupiravir): 211
- Paxlovid: 1,180
- Renal Paxlovid: 105
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Important Updates
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New FDA releases important information about risk of COVID-19 due to certain variants not neutralized by Evusheld
FDA is closely monitoring the emergence of the XBB.1.5 subvariant. This SARS-CoV-2 Omicron variant is currently estimated to account for 28% of circulating variants in the U.S.
Because of its similarity to variants that are not neutralized by Evusheld (e.g., XBB), FDA does not anticipate that Evusheld will neutralize XBB.1.5. This means that Evusheld may not protect against developing COVID-19 for individuals who have received Evusheld and are later exposed to XBB.1.5. However, we are awaiting additional data to verify that Evusheld is not active against XBB.1.5. We will provide further updates as new information becomes available.
Healthcare providers should inform individuals of the increased risk, compared to other variants, for COVID-19 due to SARS-CoV-2 variants not being neutralized by Evusheld.
If signs and symptoms of COVID-19 occur, advise individuals to test for COVID-19 and seek medical attention, including starting treatment for COVID-19 as appropriate (FDA, January 6, 2023).
Evusheld
- Evusheld EUA fact sheet
- ~ 93% projected resistance nationally
- Breakthrough infections are possible, advise patients to have a treatment plan and to seek timely medical attention if symptoms occur.
- This is important messaging to both patients that received Evusheld previously and patients getting first dose
- Evusheld shelf-life extensions
- Evusheld re-dosing
- The AstraZeneca Call Center remains available should you have questions regarding the updated dosing guidance and/or the shelf-life extension for Evusheld. The AstraZeneca Call Center can be reached at 1-800-236-9933. Evusheld can also be directly ordered in small quantities for individual providers through this form: OrderEvusheld.com
Paxlovid
Lagevrio
NEW! COVID-19 Convalescent Plasma (CCP)
Veklury® (Commercial Product)
Additional Resources
- If you are needing additional assistance with provider registration, ordering, or any other process related to therapeutics, please fill out the Office Hours Request Form to select office hour availability
- The federal government has released the Test to Treat Locator to make it easier to find Test to Treat (T2T) sites and where to send prescriptions to be filled
- For additional guidance on the new ordering process, cadence, and reporting utilization, please review our Provider Operations Manual
- For additional federal updates, shelf-life extensions, and more, please visit the ASPR webpage
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 Placing Requests
Product Case Size
Each product has a specific case size and is outlined below. When ordering, please consider the case size and order accordingly to ensure OHA can fulfill your requests properly.
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Evusheld - 12 courses
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Paxlovid - 20 courses
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Renal Paxlovid - 5 courses
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Lagevrio (molnupiravir) - 15 courses
Cadence
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Monday - HHS notifies Oregon of our total therapeutics allotment.
NOTE: HHS informs Oregon of Evusheld’s total allotment monthly, every 4th Monday
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Wednesday - Orders received by 11:59 p.m. will be allocated for the current week
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Thursday/Friday - OHA staff will review the requests, determine allotments for each requesting site, and process via the Health Partner Ordering Portal (HPOP) by Friday.
NOTE: AmerisourceBergen anticipates shipping the products within 3-5 days of order submission.
Utilization reporting
It is crucial that each site report their utilization twice a week on Mondays and Thursdays by 11:59pm, including for any product redistributed to other sites. Under-utilization in HPoP and under-reporting will affect Oregon’s future allocations.
Track your shipment
Once your packages are shipped by Amerisource Bergen, you can track them using Track My Shipment Tool.
For oral antivirals shipment tracking, please visit your HPOP account and reference "Therapeutic Shipping."
Thank you,
COVID-19 Therapeutics
Oregon Immunization Program
OREGON PUBLIC HEALTH DIVISION
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