New Nirsevimab (Beyfortus) Reporting
 We are aware of the challenges being faced with documenting nirsevimab (Beyfortus) doses. ASIIS has a new RSV deduplication logic to allow two 100 mg nirsevimab injections from the same visit to be posted in the same patient record if the patient was 20 months or younger at the time of injection.
What You Need to Know
To report two 100 mg injections given to a patient via the HL7 reporting process, you will need to send either two separate messages with each RXA segment containing a single 100 mg injection event or one message with both RXA segments for each 100 mg injection event. Similarly, you can also enter two doses manually if the HL7 data did not get transmitted successfully, and for each dose, you would set the dose size to Full and volume to 1.0 mL to match what you gave to the patient.
Under the current logic, there is no way to distinguish a true second injection from a single injection being reported more than once. Therefore, if you only give one 100 mg injection, you will have to report it exactly once either via HL7 or manually, but not through both reporting methods.
Under the new RSV deduplication logic, the system would allow up to 2 doses posted from the same visit date. Providers have to be careful and make sure each single 100 mg dose administered is reported exactly once, regardless of how it’s reported.
Tips To Prevent Extra Nirsevimab Doses
To avoid extra nirsevimab doses being posted and decremented from your VFC inventory, do not manually add doses to patient records if your site is interfaced for electronic reporting with ASIIS. We recommend waiting sufficient time for the reported HL7 data to be fully processed in ASIIS before manually going into ASIIS and adding the records.
Resource Links:
If you have any questions or concerns, please do not hesitate to contact our team at the Bureau of Immunization Services (BIZS). HL7 and Interoperability questions can be directed to ASIIS_Electronic_Reporting@azdhs.gov. Data quality questions can be directed to ASIIS_Data_Quality@azdhs.gov or contact BIZS by phone at 602-364-3642.
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